Titlebook: Circadian Rhythms in Bacteria and Microbiomes; Carl Hirschie Johnson,Michael Joseph Rust Book 2021 The Editor(s) (if applicable) and The A

摘要

Roles of Phosphorylation of KaiC in the Cyanobacterial Circadian Clockby mixing three clock proteins, KaiA, KaiB, KaiC, and ATP, in which the phosphorylation state of KaiC exhibits robust circadian rhythm. In contrast to eukaryotic clock proteins, sometimes containing tens of phosphorylation sites, KaiC has only two phosphorylation sites, serine 431 and threonine 432,

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Insights from Mathematical Modeling/Simulations of the In Vitro KaiABC Clockempts by different groups to reproduce various experimental properties of observed clock dynamics. It is separated into a discussion of modeling the dynamics of population phosphoform state transitions to generate limit cycles, and in simulating the dynamics of KaiC hexamers and protein-protein inte

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Basic Biology of Rhythms and the Microbiomeional signals. These diurnal oscillations, in turn, impact the host’s transcriptome and multiple other physiologic functions. Emerging evidence has begun to uncover the molecular mechanisms that underlie the coordinated meta-organismal diurnal rhythmicity with crucial implications for homeostasis an

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Disease Implications of the Circadian Clocks and Microbiota Interfacevidence has shown that there is an interplay between host circadian rhythms and the gut microbiota. Host circadian rhythm impacts the structure and function of gut microbial community, while in turn the microbiota regulates the host circadian clock and metabolism. Disruption of host rhythms can have

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Carl Hirschie Johnson,Michael Joseph RustA comprehensive overview on circadian clock systems in prokaryotes.Reviews the circadian clock system in cyanobacteria - including Kai.Highlights modeling approaches and biotech applications

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