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Titlebook: Circadian Rhythms in Bacteria and Microbiomes; Carl Hirschie Johnson,Michael Joseph Rust Book 2021 The Editor(s) (if applicable) and The A

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楼主: 航天飞机
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Reasons for Seeking Information on the Molecular Structure and Dynamics of Circadian Clock Componenta-molecular-scale slowness comes from structural regulations of steric hindrance, water molecules, and .-to-. peptide isomerization in KaiC, being related on one-to-one correspondence not only to the frequency of inter-molecular-scale rhythm of KaiA/KaiB/KaiC oscillator, but also to the frequency of cellular-scale rhythms.
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Insights from Mathematical Modeling/Simulations of the In Vitro KaiABC Clockic complexes and protein-protein interactions, and direct numerical simulations of biochemical reactions which incorporate thousands of combinatorial states and their transitions, including the effects of stochasticity (noise) on the simulated dynamics.
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Basic Biology of Rhythms and the Microbiome its environment, and how commensals diurnally modulate host biology in health and disease. Finally, current challenges, open questions, and perspectives in this exciting new field of chronobiology are discussed.
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