Titlebook: Chronic Obstructive Pulmonary Disease; P. M. A. Calverley (Consultant Physician, Senior F Book 1995 Springer Science+Business Media Dordre

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Imaging,the advent of computed tomography (CT) and high resolution computed tomography (HRCT) which currently provide the most sensitive and specific means of diagnosing generalized emphysema .. In addition a variety of dynamic imaging techniques give pathophysiologic information.

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Bronchodilators: Basic Pharmacology, affect other cell types. This chapter discusses the molecular, biochemical and clinical pharmacology of bronchodilators currently used in the treatment of COPD and also describes some novel bronchodilators under development.

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Epistemic and Disciplinary Reflexivity,to a wide variety of insults. Thus, a bronchial infection which would have only minor effects in a healthy individual can tip the COPD patient into frank respiratory failure. In this chapter we will review the clinical presentation and treatment of acute respiratory failure in patients with COPD.

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Reflexivity and Development Economicsition and use of the term ‘COPD’. Before proceeding, I would like to pay tribute to J.G. Scadding, whose thoughtful, rigorous work on the meaning of terms used in medicine, published over the last 3 decades, has helped enormously to clarify my thinking in this area [3–8].

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Reflexivity in Criminological Researchdies [3] was the recommendation by the Medical Research Council’s Committee on the Aetiology of Chronic Bronchitis [4] of a standardized questionnaire [5] and diagnostic criteria [6]. Chronic bronchitis thus became one of the first diseases to be defined for the purposes of epidemiologic research.

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On the Rationality of the Economic Actors,en during acute exacerbations of COPD were soon recognized [1] and led Campbell to apply new technologies to first identify the physiologic problem (hypercapnia), then hypothesize a mechanism for its production (reduced hypercapnic ventilatory drive) and finally suggest a practical solution (low flow oxgyen treatment by Venturi mask) [2].

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