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Titlebook: Chronic Lymphocytic Leukemia; Book 2005 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH,

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发表于 2025-3-21 16:48:06 | 显示全部楼层 |阅读模式
书目名称Chronic Lymphocytic Leukemia
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概述Includes supplementary material:
丛书名称Current Topics in Microbiology and Immunology
图书封面Titlebook: Chronic Lymphocytic Leukemia;   Book 2005 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH,
描述.Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of their ramifications within the fields of hematology, immunology and oncology. For a long time the Cinderella of lymphoid malignancies CLL has now become the focus of major interest and an increasing number of investigators from different areas, including genetics, molecular biology, basic and applied immunology are becoming actively engaged in the investigation of CLL. Clinicians are considering CLL as a very interesting target of many projects which aim at translating the new and exciting developments of basic science into effective new approaches to the patient. .
出版日期Book 2005
关键词Chemokine; cell; gene; gene expression; genetics; hematology; immunogloblulin; immunology; leukemia; lymphade
版次1
doihttps://doi.org/10.1007/3-540-29933-5
isbn_softcover978-3-642-06450-0
isbn_ebook978-3-540-29933-2Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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发表于 2025-3-21 21:52:36 | 显示全部楼层
David Kitchin,Adrian Quark,Jayadev Misrahe cell derivation of B-CLL and provided novel hypotheses concerning its pathogenesis. Here we summarize recent work relevant to these issues and conclude that B-CLLmay be derived from a cell that can be referred to as a marginal zone B cell. Moreover, we propose that the lack of chromosomal translo
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,The University of Chicago—1966–1972, epitopes. It is currently unclearwhether this putative antigen-driven process could occur prior to leukaemic transformation and/or that the precursors were transformed into leukaemic cells at distinct maturational stages. Themutational profile of Ig genes has been shown to be associated with diseas
发表于 2025-3-22 05:51:28 | 显示全部楼层
The Temporality of European Governance times. V-gene usage, VDJ structure, and gene expression differences in the two subgroups allowinsights into differential pathogenic mechanisms and provide further prognostic information (V3-21 usage, ZAP-70 expression). Most importantly, the . mutation status and genomic abnormalities have been sho
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New Insights into the Phenotype and Cell Derivation of B Cell Chronic Lymphocytic Leukemia,he cell derivation of B-CLL and provided novel hypotheses concerning its pathogenesis. Here we summarize recent work relevant to these issues and conclude that B-CLLmay be derived from a cell that can be referred to as a marginal zone B cell. Moreover, we propose that the lack of chromosomal translo
发表于 2025-3-22 20:05:45 | 显示全部楼层
发表于 2025-3-23 00:15:23 | 显示全部楼层
Genotypic Prognostic Markers, times. V-gene usage, VDJ structure, and gene expression differences in the two subgroups allowinsights into differential pathogenic mechanisms and provide further prognostic information (V3-21 usage, ZAP-70 expression). Most importantly, the . mutation status and genomic abnormalities have been sho
发表于 2025-3-23 02:28:50 | 显示全部楼层
0070-217X g CLL as a very interesting target of many projects which aim at translating the new and exciting developments of basic science into effective new approaches to the patient. .978-3-642-06450-0978-3-540-29933-2Series ISSN 0070-217X Series E-ISSN 2196-9965
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