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Titlebook: Chromosomal Alterations; Origin and Significa Günter Obe,Adayapalam T. Natarajan Book 1994 Springer-Verlag Berlin Heidelberg 1994 Chromosom

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书目名称Chromosomal Alterations
副标题Origin and Significa
编辑Günter Obe,Adayapalam T. Natarajan
视频video
图书封面Titlebook: Chromosomal Alterations; Origin and Significa Günter Obe,Adayapalam T. Natarajan Book 1994 Springer-Verlag Berlin Heidelberg 1994 Chromosom
描述Due to sensitive molecular biological techniques, our understanding of chromosomal aberrations is steadily increasing. Provided here is a review of basic and applied aspects of the field. Chromosome structure, induction of DNA lesions by different clastogenic agents and their repair, induction of aberrations by agents which affect specific sequences in the DNA, and factors affecting induction and yield of chromosomal aberrations are covered. .Further, topics such as automation of aberration scoring, problems associated with using chromosomal aberrations and micronuclei in population monitoring and the importance of chromosomal aberration assays in mutagenicity testing of chemicals are included.
出版日期Book 1994
关键词Chromosom; Chromosomal Aberrations; Chromosomen; Chromosomenaberrationen; DNA; Zytogenetik; chromosome; cyt
版次1
doihttps://doi.org/10.1007/978-3-642-78887-1
isbn_softcover978-3-642-78889-5
isbn_ebook978-3-642-78887-1
copyrightSpringer-Verlag Berlin Heidelberg 1994
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Synergism and Adaptive Response in the Interaction of Low Dose Irradiation with Subsequent Mutagenio a subsequent higher dose. The initial dose may protect by inducing or priming a repair mechanism. This so called “adaptive response” has been demonstrated by numerous authors using different materials and different end points (for reviews, see Kelsey et al. 1991; Liu et al. 1992; Luckey 1991; Ofte
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Implementing a Full Apache Deployment,r by reaction with water which also leads to the release of a proton. For instance the water radical cations convert into OH radicals and protons. The OH radicals diffuse to the DNA and react mainly with the bases and to a smaller extent with the sugar (Scholes et al. 1960). The organic radicals can
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Red Sanders: Silviculture and Conservationmbination, chromatid segregation and transcription (for a review see Wang 1985; D’Arpa and Liu 1989). These enzymes catalyse the interconversions between topological isomers of DNA. DNA topoisomerase I (Topo I) breaks and rejoins one strand of the DNA double helix, whereas DNA topoisomerase II (Topo
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Chromatin Structure, Hyperthermia and Repair of UV-Induced DNA Photolesions in Mammalian Cells,atin along nucleoskeleton associated repair enzymes. Perhaps nucleoskeleton-centred repair may be confined only to biological important domains comprising active genes. Results of experiments aimed to discover nucleoskeleton-centred repair point to the existence of such a mechanism for transcriptionally active DNA.
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