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Titlebook: Cholesterol Crystals in Atherosclerosis and Other Related Diseases; George S. Abela,Stefan Mark Nidorf Book 2023 The Editor(s) (if applica

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书目名称Cholesterol Crystals in Atherosclerosis and Other Related Diseases
编辑George S. Abela,Stefan Mark Nidorf
视频video
概述The first authoritative book dedicated to the understanding of cholesterol and its effect on the body.Provides a comprehensive overview of cholesterol crystal formation and methods for detection and t
丛书名称Contemporary Cardiology
图书封面Titlebook: Cholesterol Crystals in Atherosclerosis and Other Related Diseases;  George S. Abela,Stefan Mark Nidorf Book 2023 The Editor(s) (if applica
描述This book is the first authoritative and comprehensive text dedicated to the understanding of how cholesterol triggers vascular inflammation and mechanical injury that leads to heart attacks, strokes as well as other organ and tissue pathology. It includes chapters on the background of cholesterol crystal formation and methods for their detection as well as a description of the physiochemical transformation of metastable ‘liquid’ cholesterol to a solid flat plate crystalloid within the cellular and extracellular environment resulting in volume expansion. Chapters also discusses cholesterol crystals and other crystalloid molecules found in atherosclerotic plaque. In addition, the book examines how cholesterol crystals can induce similar injurious processes in other organs including the retina of the eye to cause blindness, in solid cancers causing further tumor growth and in the brain of patients with Alzheimer’s. And lastly, the book addresses various potential therapeutics that disrupt the physiochemical transformation of cholesterol from a liquid to a solid, inhibit its role in triggering inflammation and tissue injury while ushering a path towards targeted therapies..Cholesterol
出版日期Book 2023
关键词Cholesterol Crystals; Cholesterol Crystal Formation; Crystal Formation; Atherosclerosis; Vascular Inflam
版次1
doihttps://doi.org/10.1007/978-3-031-41192-2
isbn_softcover978-3-031-41194-6
isbn_ebook978-3-031-41192-2Series ISSN 2196-8969 Series E-ISSN 2196-8977
issn_series 2196-8969
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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In Vivo Detection of Cholesterol Crystals in Atherosclerotic Plaque with Optical Coherence Tomographtical coherence tomography (OCT). Although OCT mostly detects large aggregates of CCs, this evidence provides clear support for the belief that CCs develop in vivo in stable plaques, and that their presence in the plaque core has prognostic significance over and above other morphologic features of a
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Detecting Cholesterol Crystals Clinically in Spontaneous Aortic Plaque Ruptureflammasome. With the accumulation of asymptomatic injuries due to silent embolisms, which may be related to aging and chronic inflammation, the need for accurate and precise diagnostics should be considered crucial.
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Atherosclerotic Plaque Morphology and the Conundrum of the Vulnerable Plaque risk of future injury, most such plaques remain stable..Together these observations indicate that the vulnerability of plaques is dynamic and raises the possibly that instability relates to ongoing changes in the physiochemistry of the lipid core that at times favors the formation of cholesterol cr
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The Role of Cholesterol Crystals in the Development and Progression of Degenerative Valve Diseaserated to slow the degenerative process in previously normal valve leaflets but does not slow valvular sclerosis once it is in train. This suggests that over time the inflammatory processes induced by cholesterol crystals entrapped in the valve matrix become the main drivers of valvular degeneration,
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Rechnernetze in der Bundesrepublikinjury in the vascular bed leads to sclerosis, calcification, and neovascularization of the arterial wall and predisposes to erosion and rupture of the plaque cap that lead to atherothrombotic events and CC embolization..Thus, inhibiting the formation of cholesterol crystals, dissolving them, and in
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