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Titlebook: Chiral Separations; Methods and Protocol Gerald Gübitz,Martin G. Schmid Book 2004 Humana Press 2004

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https://doi.org/10.1007/978-3-031-29834-9 a drug with a chiral center should be known and the quantitative isomeric composition of the material used in pharmacologic, toxicologic, and clinical studies known. Specifications for the final product should assure identity, strength, quality, and purity from a stereochemical viewpoint.”
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Conclusion: Reflecting on the RMA Concept,sis (CE) using (+)−18-crown-6-tetracarboxylic acid (.) as a chiral selector added to the electrolyte for the chiral separation of amino acids. This crown ether was shown to be applicable also to the chiral separation of dipeptides (.,.) (.), sympathomimetics (.) (.), and various other drugs containing primary amino groups (.) by CE.
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Separation of Racemic Trans-Stilbene Oxide by Sub-/Supercritical Fluid Chromatography, a drug with a chiral center should be known and the quantitative isomeric composition of the material used in pharmacologic, toxicologic, and clinical studies known. Specifications for the final product should assure identity, strength, quality, and purity from a stereochemical viewpoint.”
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Separation of Enantiomers by Capillary Electrophoresis Using Cyclodextrins,oyed chiral selectors, since their first application in isotachophoresis (.). The application of CDs for capillary zone electrophoresis was pioneered a one year later by Fanali (.) for chiral separation of symphatomimetic drugs.
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