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Titlebook: Chikungunya Virus; Advances in Biology, Chioma M. Okeoma Book 2016 Springer International Publishing Switzerland 2016 CHIKV.host response.p

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k of effective treatment/therapy, efficient control of transmission, and knowledge about mechanisms of pathogenesis. Additionally, globalization of CHIKV is predicated on its mode of dissemination (978-3-319-82704-9978-3-319-42958-8
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Epidemiological History of Chikungunya Virus,zootic cycle, on-going, low-level activity is typical with large periodic urban outbreaks. The epidemiology of CHIKV since its re-emergence in 2004 in coastal Kenya has been characterized by large attack rates, rapid movement and geographic expansion, utilization of alternate mosquito vectors, and a
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Chikungunya Virus Pathogenesis,ng the last 10 years has resulted in new investigations of CHIKV biology and pathogenesis in humans and animal models. In this chapter, we present the most recent advances in our understanding of acute and chronic CHIKV pathogenesis.
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