Titlebook: Chemotherapy; Frederick F. Becker Book 1977 Plenum Press, New York 1977 brain tumors.breast cancer.cancer.cell.chemotherapy.classification

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PACK

从容

Folate Antagonistsesponsible for toxicity to malignant tissue, i.e., inhibition of dihydrofolate reductase. Significant injury to the liver, brain, and kidneys has also been seen as a consequence of antifolate therapy. These latter toxicities, which are not clearly related to reductase inhibition, will be considered later in this chapter.

蜿蜒而流

Hydrazines and Triazenesvide a limited stability to the respective molecules. While a large number of derivatives in both groups have been synthesized and evaluated for biological activity, the representatives reported in this chapter are few, and are the most interesting ones from both the therapeutic and the theoretical points of view.

Affable

Semiclassical Roles for Classical Orbits,cause of the absorption or inactivation, or both, of the drug on passage through the arterial bed. Although the procedure is technically more difficult, effluent drug-containing blood has been diverted from the systemic circulation or prevented from reaching sensitive normal tissues during the drug infusion.

苦恼

Seizure

bacterial disease, and, therefore, its failures were felt all the more. Despite the serendipitous discoveries and inspired insights which tantalized us with striking remissions, or the rare tumors which proved to be fully susceptible to a given agent, in the main, there has been either total failur

议程

Postulate

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