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Titlebook: Chemokine Roles in Immunoregulation and Disease; P. M. Murphy,R. Horuk Conference proceedings 2004 Springer-Verlag Berlin Heidelberg 2004

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Grundvorstellung der Quantenphysik, molecular weights in the range of 7–15 kDa, and are synthesized with a leader sequence of 20–25 amino acids, which is cleaved off before release. Two main subfamilies, CXC and CC chemokines, are distinguished according to the position of the first two cysteines, which are adjacent (CC) or separated
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https://doi.org/10.1007/978-3-322-83917-6s, over 40 distinct human chemokines have been identified (Rossi and Zlotnik 2000). In general, chemokine number and diversity increase as organisms climb the evolutionary ladder, suggesting that this protein family evolved pari passu with specialized leukocyte subtypes in order to control their spe
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https://doi.org/10.1007/978-3-322-84443-9onstitute 1%–2% of circulating leukocytes. However, a large proportion of the eosinophils of the body are resident in walls of the gastrointestinal tract. The bone marrow also contains a reserve of immature and mature eosinophils. Eosinophils are thought to have evolved as effector cells in host def
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Beruflicher Weiterbildungsbereichhoming (Baggiolini et al. 1997, 1998). They function by binding to seven transmembrane G-protein coupled receptors, inducing conformational changes that trigger a cascade of signaling pathways. In turn these signaling events produce cytoskeletal rearrangements, increased adhesiveness, and cell migra
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https://doi.org/10.1007/978-3-322-84443-9st family of secreted intercellular messengers, having over 43 members recognized at this time. The family is characterized by the presence of four positionally conserved cysteine residues and subdivided into four branches based on the relationship of the two amino-proximal cysteines: C-C, C-X-C, C-
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https://doi.org/10.1007/978-3-662-05403-1Asthma; Chemokine; Chemokines; Immunology; Multiple Sclerosis; Receptors; Regulation; Structure/function
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