Titlebook: Chemistry and Biological Actions of 4-Nitroquinoline 1-Oxide; Hideya Endo,Tetsuo Ono,Takashi Sugimura Book 1971 Springer-Verlag Berlin · H

Crumple

meritorious

一美元

Microaneurysm

懒惰民族

Quick-Turnaround ASIC Design in VHDLAlthough 4-nitroquinoline 1-oxide is now known as one of the potent carcinogens, the first interest in the biological property of this compound arose out of its strong antibacterial (. and ., 1952) and antifungal activities (., 1953), and this interest has rapidly developed to include its mutagenic and carcinostatic activities.

Allergic

Quantitative Computed Tomography,In 1955, . applied the chemical to a fungus, ., in the hope of inducing mutants. This served as trigger to start a new road of microbiology with 4-nitroquinoline 1-oxide.

箴言

Introduction,4-Nitroquinoline 1-oxide was first synthesized by . and his collaborators in 1942 and the carcinogenicity of this compound was established in 1957 by . and his colleagues at the Cancer Institute, Japanese Foundation for Cancer Research.

小虫

Carcinogenicity,The powerful carcinogenic action of 4-nitroquinoline 1-oxide was first demon-strated by ., . and . in 1957. Since then more than 60 reports have been presented on the carcinogenic action of this compound and its derivatives, details of which are summarized in Table 1.

易于交谈

Metabolism,It is generally accepted that carcinogenic substances administered to animals are converted metabolically . into the active compounds, which are the true carcinogens and are called proximate carcinogens.

Awning

Anti-tumor Effect,Although 4-nitroquinoline 1-oxide is now known as one of the potent carcinogens, the first interest in the biological property of this compound arose out of its strong antibacterial (. and ., 1952) and antifungal activities (., 1953), and this interest has rapidly developed to include its mutagenic and carcinostatic activities.