Titlebook: Chemical Mutagens; Principles and Metho Alexander Hollaender Book 1973 Plenum Press, New York 1973 DNA.Fixation.Handling.Mamma.Xeroderma pi

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perjury

Observations on Meiotic Chromosomes of the Male Mouse as a Test of the Potential Mutagenicity of Chand demonstrative method to routinely test potential mutagenicity in mammals. Such studies were made possible by recent technical advances in methods of making meiotic preparations from mammalian testes which provide a large number of analyzable cells and allow the scoring of many cells per animal and per testis.

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Techniques for Monitoring and Assessing the Significance of Mutagenesis in Human Populations,ot only the problem of detecting increases in mutation rate, but also that of assessing their significance in terms of human health. The latter of these two related problems is more difficult than is generally recognized.

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Tradescantia Stamen Hairs: A Radiobiological Test System Applicable to Chemical Mutagenesis,2) somatic mutations in petals and stamen hairs in clones heterozygous for flower color; (3) pollen abortion; (4) loss of reproductive integrity in stamen hairs; and (5) whole plant or seedling death. The stamen hairs of . clone 02 have also proved to be sensitive to radiation-induced mutations at doses in the millirad region..

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Immunization

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Specific-Locus Mutational Assay Systems for Mouse Lymphoma Cells, Based on this knowledge, it became easy to understand how Szybalski and Morrow failed to demonstrate an enhancement of mutant frequency upon treatment of cells with mutagens; i.e., the background mutant frequency was too high to observe an increase arising from the induction of new mutants.

Morose

Insect Chemosterilants as Mutagens,ed to fulfill, the search for new chemosterilants was oriented primarily to finding and identifying selective types of cytotoxicity. A brief historical summary will clarify the reason for this orientation.

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