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Titlebook: Characterization of Proteins; Felix Franks Book 1988 Springer Science+Business Media LLC 1988 amino acid.biosensor.enzymes.membrane recept

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书目名称Characterization of Proteins
编辑Felix Franks
视频video
丛书名称Biological Methods
图书封面Titlebook: Characterization of Proteins;  Felix Franks Book 1988 Springer Science+Business Media LLC 1988 amino acid.biosensor.enzymes.membrane recept
描述Proteins are the servants of life. They occur in all component parts of living organisms and are staggering in their functional var- ty, despite their chemical similarity. Even the simplest single-cell organism contains a thousand different proteins, fulfilling a wide range of life-supporting roles. Their production is controlled by the cell’s genetic machinery, and a malfunction of even one protein in the cell will give rise to pathological symptoms. Additions to the total number of known proteins are constantly being made on an increasing scale through the discovery of mutant strains or their production by genetic manipulation; this latter technology has become known as protein engineering. The in vivo functioning of proteins depends critically on the chemical structure of individual peptide chains, but also on the detailed folding of the chains themselves and on their assembly into larger supramolecular structures. The molecules and their fu- tional assemblies possess a limited in vitro stability. Special methods are required for their intact isolation from the source material and for their analysis, both qualitatively and quantitatively. Proteins are also increasingly used as “
出版日期Book 1988
关键词amino acid; biosensor; enzymes; membrane receptor; protein; protein engineering; proteins; receptor
版次1
doihttps://doi.org/10.1007/978-1-59259-437-5
isbn_softcover978-1-4899-4113-8
isbn_ebook978-1-59259-437-5
copyrightSpringer Science+Business Media LLC 1988
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Protein and Peptide Hormones, will not be dealt with in the present chapter, in which the old-fashioned definition of hormones (chemical messengers acting at a distance) will be accepted by default: It is true more often than not.
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Characteristics of Proteins and Peptides ,,ar environment. I have in mind, for example, the phospholipids of the cell membrane, nonproteinacious chemical messengers (steroids and neurotransmitters), and drugs and toxins of low molecular weight.
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Preparative Liquid Chromatography,ivity, and this imposes severe restraints upon the operating system. Three effects can be listed that potentially can affect protein denaturization: (.) the “hardness” of the surface, (.) temperature effects, and (.) shear forces.
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