Titlebook: Characterization of Nanoparticles Intended for Drug Delivery; Scott E. McNeil Book 2018Latest edition Springer Science+Business Media LLC

OMIT

PEG Quantitation Using Reversed-Phase High-Performance Liquid Chromatography and Charged Aerosol Detssolution of colloidal gold nanoparticles by potassium cyanide (KCN) and the other by displacement of PEG by dithiothreitol (DTT). The methods outlined herein were applied to 30 nm colloidal gold grafted with 20 kDa PEG, but they can be easily adapted to any size colloidal gold nanoparticle and PEG chain length.

混合

Throttle

Imaging of Liposomes by Transmission Electron Microscopycan be imaged directly in the electron microscope under liquid nitrogen temperature. Although subject to artifacts, negative staining TEM can also be a useful method to image liposomes, as it is faster and simpler than cryo-EM, and requires less advanced equipment.

cogent

Elemental Analysis in Biological Matrices Using ICP-MS biological matrices, ensuring complete homogenization of tissues, and outlines the preparation of appropriate standards and controls. The method described herein utilized gold nanoparticle-treated samples; however, the method can easily be applied to the analysis of other metals.

样式

Quantitation of Surface Coating on Nanoparticles Using Thermogravimetric Analysise of the nanoparticle. TGA experiments run under inert atmosphere can also be used to determine residual metal content present in the sample. In this chapter, the TGA technique and experimental method are described.