Titlebook: Challenges in Pediatric Kidney Transplantation; A Practical Guide Katherine E. Twombley Book 2021 The Editor(s) (if applicable) and The Aut

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Challenges Surrounding Induction Protocols in Childrenset of early acute rejection but also to maximize the longevity of the graft by minimizing the use of potentially toxic maintenance agents while preventing early immunologic insults. With the development of the field and the expansion of transplant immunotherapies, induction agents have changed over

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Post-transplant Medication Challengesiatric kidney transplantation. As significant improvements have been established in short-term survival over the last few decades, particularly with the introduction of calcineurin inhibitors, the focus remains on the ideal immunosuppressive regimen needed to optimize long-term allograft survival. A

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Multiorgan Transplantation Challengeseart, liver, and gastrointestinal tract. Multiorgan transplant is a lifesaving procedure for children with multiorgan failure, yet in practice it can be challenging due to lack of clarity about the most appropriate timing and perioperative management strategies. The role of simultaneous versus seque

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Katherine E. TwombleyReviews the challenges faced during each stage of the kidney transplantation process.Features high yield case presentations of typical pediatric transplant scenarios.Written by experts in the field

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Tartan Enactments and Performing Hybridity,preparation, surgical techniques, immunologic management, and post-transplant monitoring. The immune system in children evolves continuously, which impacts their pre-transplant evaluation and post-transplant outcomes. In this chapter, we explore the human leukocyte antigen (HLA) system and consider

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Tartan Enactments and Performing Hybridity, is limited by ongoing and silent immunologic and non-immunologic injury processes. This is especially important in children, who have longer expected life span than adults and are at higher risk of rejection due to greater immunologic response in early ages and to a higher rate of non-adherence dur