Titlebook: Cervical Cancer; Jaime G. de la Garza-Salazar,Flavia Morales-Vásque Book 2017 Springer International Publishing Switzerland 2017 cervical

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Primary Surgical Treatment of Cervical Cancer,sults. Additionally, the sentinel lymph node biopsy in cervical cancer is beginning to be incorporated as an alternative to BPL. Moreover, new techniques that preserve fertility are now used in strictly selected young women who would like to have more children.

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Surgical Treatment for Advanced or Recurrent Disease in Cervical Cancer,tinal tracts can diminish the need for stomas and, along with vaginal reconstruction, can significantly improve quality of life for many patients afterexenteration. These advances in surgery and radiotherapy help make the procedure a viable option for patients with otherwise incurable elvic malignan

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Systemic Treatment of Cervical Cancer,studies in metastatic and/or recurrent cancer suggest that new signaling pathways in CC can be explored to identify novel molecular targeted therapies in order to obtain better outcomes for patients with this disease..Some of the therapies for infrequent histologic types are also briefly reviewed.

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Immuno-Oncology in Cervical Cancer,ess. It is clear that the adaptive immune system plays an important role in CC; multiple studies have shown that immune infiltration is related to prognosis. Non-viral targets are also potential candidates for targeting by next-generation immunotherapies for CC and vaccines to prevent relapse.

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Introduction,s referred to as first world countries early detection and treatment has given positive long-term results in women with CxCa. In Western Europe, Australia and New Zealand, for every 100,000 women diagnosed at least two will die from this disease. According to the WHO, in eastern Africa the amount of

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Cervical Cancer Epidemiology,world, representing approximately 9 of every 10 deaths in less developed regions (87%). In Mexico, its relevance is also considerable; it is the neoplasia with the second highest incidence rates and the second leading cause of death among women of all ages. The most affected age groups are from 50–5

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Malignant Transforming Mechanisms of Human Papillomavirus, in a tissue. High-risk-HPV-infected cells and carcinogenesis progression are terminal events, since cancer cells contain integrated HPV genomes and do produce viral progeny. High-risk HPV (HR-HPV) genome integration indeed represents a consequence of HPV E6/E7- induced genomic instability. HR-HPV E

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Transcriptome Studies Reveal Altered Signaling Pathways in Cervical Cancer,sed genes constitutes an initial step in this type of analysis. The integration of the information acquired by these global expression profiles regarding signaling pathways or organized modules that work according to specific cellular responses has made it possible for us to understand the developme