Titlebook: Cerebrospinal Fluid Disorders; Lifelong Implication David D. Limbrick Jr.,Jeffrey R. Leonard Book 2019 Springer Nature Switzerland AG 2019

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Physiopathology of Foetal Onset Hydrocephalusions and certain foreign signals all convey into a final common pathway leading to a cell junction pathology of cells lining the ventricular walls (ventricular zone, VZ). The early disruption of the VZ of the embryonic telencephalon implies the loss of neural stem cells (NSC) and abnormal neurogenes

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Intracranial Pulsatility, Cerebrospinal Fluid Flow, and Glymphatic Function in Idiopathic Normal Prenction capacity of the brain may be examined by magnetic resonance imaging (MRI) utilizing a MRI contrast agent administered to the CSF space (e.g. intrathecally) to serve as a CSF tracer (gMRI). Using this approach, evidence has been given that individuals with impaired ICC may have reduced clearan

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Congenital Hydrocephalusan vertebrates. A comprehensive understanding of the key genetic drivers and the associated molecular mechanisms of CH might help identify targets for the development of novel therapeutics for this disorder of cerebrospinal fluid (CSF) homeostasis.

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Genetics of Hydrocephalus: Causal and Contributory Factors We next address syndromes in which hydrocephalus may be an accompanying – but not the primary – clinical feature. Finally, we touch upon the notion of genetic variants that are not pathogenic in themselves, but could increase the likelihood of developing hydrocephalus in the presence of other risk

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Anatomy and Physiology-Based Magnetic Resonance Imaging in Hydrocephalus examines the evolution of magnetic resonance neuroimaging technology in hydrocephalus. We particularly focus on the use of anatomy and physiology-based imaging techniques and diffusion tensor imaging which are supported by a growing body of literature as promising noninvasive tools in the diagnosis

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Posthemorrhagic Hydrocephalus-related mortality rates in premature infants with IVH. However, mortality rates of premature infants with severe IVH remain high. Additionally, patients with severe IVH and PHH frequently exhibit neurocognitive impairment and elevated risks of developing cerebral palsy or epilepsy (Adams-Chapman et

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Hydrocephalus Secondary to Spina Bifida CSF diversion. As with other hydrocephalus variants, patients suffering from hydrocephalus secondary to MM are living longer and require long-term surveillance and management by a multidisciplinary team of surgical, neurologic, and physiatric specialists.

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