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Titlebook: Cerebrospinal Fluid Analysis in Multiple Sclerosis; E. J. Thompson,M. Trojano,P. Livrea Conference proceedings 1996 Springer-Verlag Italia

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书目名称Cerebrospinal Fluid Analysis in Multiple Sclerosis
编辑E. J. Thompson,M. Trojano,P. Livrea
视频video
图书封面Titlebook: Cerebrospinal Fluid Analysis in Multiple Sclerosis;  E. J. Thompson,M. Trojano,P. Livrea Conference proceedings 1996 Springer-Verlag Italia
描述In the spring of 1993 a meeting of the European Charcot Foundation was held in Bari as it was quite clear that there was a renaissance of Italian interest in cerebro­ spinal fluid. Two of the influential figures with a long-standing commitment to this field were Professor Paolo Livrea and Dr. Maria Trojano. At this meeting we con­ sidered the possibility of collecting together the various papers which had been presented, however the idea evolved further to the present volume, which incor­ porates a broader view. This starts with the anatomical approach, including neuro­ pathology, CSF cells and MRI correlations. It also includes virology, physiology of the blood-CSF barrier and the immunology of intrathecal responses. It further con­ siders the relevance of the CSF parameters to therapy. Finally, the importance of quality assurance and handling of the precious fluid is discussed. The original plan was to have the book published in Italian, but we are grateful to the publishers for allowing English text, in order to have a wider, international audience. As is fate of any book, interest in this area has been accelerated considerably; nevertheless we hope this provides a summary from
出版日期Conference proceedings 1996
关键词information; magnetic resonance imaging (MRI); multiple sclerosis; myelin; nervous system; neuropathology
版次1
doihttps://doi.org/10.1007/978-88-470-2205-8
isbn_softcover978-88-470-2207-2
isbn_ebook978-88-470-2205-8
copyrightSpringer-Verlag Italia 1996
The information of publication is updating

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https://doi.org/10.1007/978-3-8348-9466-3iation, basic information is provided from proteins in CSF, in particular by detection of intrathecally synthesized immunoglobulin fractions in CSF. For the most sensitive quantification of a brainderived CSF protein fraction, besides the corresponding blood-derived fraction in CSF we need to take i
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https://doi.org/10.1007/978-3-8348-9466-3filtration and demyelination. It is widely accepted that an “activation” of CNS microvascular endothelial cells (EC) associated with blood-brain barrier (BBB) damage represents early event in demyelinating lesion development [1, 2]. However, the mechanisms responsible for the migration of lymphocyte
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https://doi.org/10.1007/978-3-8348-9466-3y short lifetime, act mainly as autocrine/paracrine growth/immunomodulating factors, and are absorbed instantly at the tissue/cell target level by high affinity receptors (the biological features of cytokines are summarized in Table 1).
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https://doi.org/10.1007/978-3-8348-9466-3peutic agents in MS are: corticosteroids, cyclophosphamide, azathioprine, cyclosporine, interferon, total lymphoid irradiation, plasma exchange, monoclonal antibodies, copolymer-I and immunoglobulins. Modes of administration are: oral, intramuscular, intravenous or intrathecal; administration of dru
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