书目名称 | Central Nervous System Metastasis, the Biological Basis and Clinical Considerations | 编辑 | Diane Palmieri | 视频video | | 概述 | Comprehensive resource of both biology and clinical knowledge of CNS metastasis.Only current book to cover the biology in depth, most cover clinical management of the disease.Topics covered by leaders | 丛书名称 | Cancer Metastasis - Biology and Treatment | 图书封面 |  | 描述 | .This volume will cover what is known regarding the biology and treatment of CNS metastasis, including novel chapters such as the future of targeted therapies. It will begin with an overview of the natural history and risk factors for CNS metastases that will broadly cover all cancer histologies. This will be followed by 3 chapters that will cover the biology. These include: molecular biology, discussing what is known about specific genes/proteins involved in the process and model systems to study brain metastasis; the brain microenvironment, focusing on how it is different from the microenvironment of other organs of the body; and the blood-brain barrier, which includes a discussion of permeability with respect to brain metastases. A chapter on experimental imaging will cover both the biology of brain metastasis from an imaging perspective and use of imaging techniques to study brain metastases. The clinical chapters will discuss treatment options with separate chapters on surgery, chemotherapy and radiation. In addition, leptomeningeal metastasis will be given its own chapter. Finally, quality of life issues will be the concluding chapter.. | 出版日期 | Book 2012 | 关键词 | Biology; Brain; CNS Metastasis; Metastasis | 版次 | 1 | doi | https://doi.org/10.1007/978-94-007-5291-7 | isbn_softcover | 978-94-017-8201-2 | isbn_ebook | 978-94-007-5291-7Series ISSN 1568-2102 Series E-ISSN 2215-1648 | issn_series | 1568-2102 | copyright | Springer Science+Business Media Dordrecht 2012 |
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