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Titlebook: Central Nervous System Intraoperative Cytopathology; César R. Lacruz,Javier Saénz de Santamaría,Ricardo Book 20141st edition Springer Scie

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Tumors of the Pineal Region,method of choice for obtaining diagnostic tissue. Cytologic features of PPT are quite different. Pineoblastoma shows an undifferentiated appearance similar to that of embryonal tumors, whereas pineocytoma resembles central neurocytoma with round, uniform pineocytic cells.
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Non-neoplastic Disorders,ells and macrophages, obscured in frozen sections, are nicely preserved in smears. The presence of large number of inflammatory cells or abundant macrophages virtually rules out the diagnosis of neoplasia and leads the diagnosis in the direction of reactive/inflammatory processes, organizing infarct, or demyelinating disease.
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Reactions of Imidoselenium Compounds,Despite technologic advances in neuroradiology and neurosurgery, intraoperative consultation is essential for evaluating CNS lesions and providing firm grounds for decision making and guide therapeutic management of patients with CNS lesions. Cytology is a rapid diagnostic modality with >90 % diagnostic accuracy.
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Carl-Henrik Heldin,Bengt WestermarkIntraoperative cytology consultation in neuropathology is a process that must be preceded by adequate clinical and radiologic evaluation. An adequate sample requires an adequate squash/smear preparation technique, and adequate H&E or Papanicolaou and Romanowsky stains.
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Mutational Analysis of v-, Oncogene FunctionAt the time of evaluating the smear, it is necessary to become familiar with the normal cytologic appearance of the different brain regions. It is also extremely useful to recognize the cytologic features of reactive gliosis.
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Miles V. Klein,Thomas E. FurtakFor the study of astrocytic tumors, it is advisable to divide them in diffuse astrocytoma, anaplastic astrocytoma, glioblastoma, pilocytic astrocytoma, and other special astrocytomas. The fibrillary appearance of the background is the most relevant cytologic feature of all astrocytic tumors.
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