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Titlebook: Cellular and Molecular Biology of Myelination; Gunnar Jeserich,Hans H. Althaus,Thomas V. Waehneld Conference proceedings 1990 Springer-Ver

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Distribution of Myelin Protein Gene Products in Actively-Myelinating Oligodendrocyteslly feasible areas of research in neurobiology. Myelination occurs throughout the neuroaxis and myelin-specific gene products are abundant and well-characterized. Translational products of myelin genes are assembled into ultrastructurally distinct membranes in an orderly and predictable manner. The
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Some Aspects of Mechanisms of Inflammatory Demyelinationelitis (RAE). Both are characterized by perivascular inflammation, edema, demyelination and reactive gliosis. In MS the formation of the lesion, which contains T-lymphocytes and macrophages, is generally acknowledged to be related to a cell-mediated immune (CMI) response, and it is known that EAE in
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Tellurium-Induced Demyelinationis one of the few such non-immunological models available. Other models may result in an asynchronous patchwork of demyelinating and remyelinating segments (., lead intoxication), or are localized to very discrete regions (., demyelination induced by topical application of lysolecithin or diphtheria
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The Transplantation of Glial Cells into Areas of Primary DemyelinationGraça and Blakemore, 1986). This lesion therefore provides a system in which one can examine interactions between axons and glia which are involved in the reconstruction of a CNS environment around axons. By injecting glial cell cultures of differing composition it is possible to examine the ability
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