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Titlebook: Cellular and Molecular Approaches to Regeneration and Repair; Paul A. Lapchak,John H. Zhang Book 2018 Springer International Publishing AG

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发表于 2025-3-21 16:16:23 | 显示全部楼层 |阅读模式
书目名称Cellular and Molecular Approaches to Regeneration and Repair
编辑Paul A. Lapchak,John H. Zhang
视频video
概述Stem cell therapy and molecular approaches.Covers the topic from lab work to clinical trial design.Contributions from some of the leading researchers in the field.Includes supplementary material:
丛书名称Springer Series in Translational Stroke Research
图书封面Titlebook: Cellular and Molecular Approaches to Regeneration and Repair;  Paul A. Lapchak,John H. Zhang Book 2018 Springer International Publishing AG
描述.This book discusses recent advances in the field of translational stroke research. The editors have designed the book to provide new insight into the importance of regeneration and repair mechanisms for stroke victims. The editors have brought together a talented group of international stroke researchers and clinicians to contribute to this volume, which is written for students, researchers and physicians in biotechnology, neurosciences, neurology, neuroradiology and neurosurgery..Throughout the world, stroke is still a leading cause of mortality and morbidity; there are 152,000 strokes in the United Kingdom, 62,000 in Canada, and approximately 15 million people worldwide. L.arg.e. c.om.m.uni.ties of .stro.k.e. .survivo.r.s. .are. eage.r.l.y aw.a.i.t.ing scientific. a.dv.ance.s. i.n. tra.nslati.o.n.a.l. .stroke. re.s.earc.h. related to regeneration and recovery of function that .would. .o.ffe.r. .n.e.w. .t.he.r.ape.ut.ic.s. for re.h.a.bi.l.i.tati.on. and regeneration. utilizing novel stem cell and molecular-based approaches. This volume will allow the reader to. .und.e.rs.nd .the future of stroke treatment from its inception in the laboratory through to clinical trial design. The
出版日期Book 2018
关键词stroke; regeneration; exosomes; stem cell therapy; neurotrophic; molecular
版次1
doihttps://doi.org/10.1007/978-3-319-66679-2
isbn_softcover978-3-319-88299-4
isbn_ebook978-3-319-66679-2Series ISSN 2363-958X Series E-ISSN 2363-9598
issn_series 2363-958X
copyrightSpringer International Publishing AG 2018
The information of publication is updating

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https://doi.org/10.1007/978-3-540-77107-4ntly with age both in men and women with incidence rates accelerating above 70 years. Since stroke afflicts mostly the elderly comorbid patients it is highly desirable to test the efficacy of cell therapies in an appropriate animal stroke model. It has been noted that the potential for neurogenesis
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https://doi.org/10.1007/978-3-540-77647-5te gyrus. Following cerebral insults, they are mobilized from their niches to engage in regeneration and mediate functional recovery. After cerebral ischemia, eNSC generate new neurons in a process called neurogenesis, but also indirectly mediate regeneration via pleiotropic functions including neur
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Optimal Control of Nonlinear Processesral cell death occurs after exposure to blood metabolites or subsequently damaged cells. Based on these disappointing results of 1026 neuroprotective agents, researchers turned their interests on neurogenesis, which is traditionally considered as an endogenous neuroprotective mechanism after acute c
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Optimal Control of Nonlinear Processese to chronic therapeutic strategies in the phase of irreversible brain parenchyma damage showed until now controversial results in pre-clinical studies: currently there are no effective treatment strategies apart from neurological rehabilitation aiming at restoration of functional post-ischemic defi
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Continuous-Time Dynamical Systems window and risk for hemorrhagic transformation. Stroke is a multiphasic disease with a complex pathology. After the initial insult, a cascade of events occur causing secondary cell death and the expansion of the penumbra. The major contributing factors to this secondary cell death are depletion of
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Optimal Control of Nonlinear Processeshe road in understanding the potential clinical applications of cell therapies in stroke recovery. Cells can be obtained from multiple sources and transplanted through different routes. Animal and human studies suggest that cell therapies exert their effect via paracrine and immunomodulatory effects
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