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Titlebook: Cellular Peptidases in Immune Functions and Diseases; Siegfried Ansorge,Jürgen Langner Book 1997 The Editor(s) (if applicable) and The Aut

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-Glutamyl Transpeptidase, a Blood-Brain Barrier Associated Membrane Protein of capillaries can be distinguished: the fenestrated, the discontinuous, and the continuous type. In the continuous type the endothelial cells, which cover the inner surface of the brain capillaries, build up a dense surface. In consequence, there is no possibility for free exchange of blood solutes to the central nervous system.
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Specific Inhibitors of Aminopeptidase P the metal-dependent peptidases leucine aminopeptidase (LAP), aminopeptidase B and aminopeptidase M.. X-ray crystallografic results demonstrated the bestatin chelation of one of the active Zinc ions of bovine lens LAP.’ Bestatin seems to be a natural mimetic of the tetrahedral intermediat of LAP-catalyzed substrate hydrolysis.
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Organometallic Chemistry and Catalysisified in the last eight years; more than for any other protease classes, i.e., the serine/threonine, cysteine, or aspartic classes of proteases (see the Peptidase World Wide Web sites:http://www.qmw.ac.uk/~ugca000/iupac/enzyme/ and htpp://prolysis.phys.univ-tours.fr/Prolysis). In 1987, the primary a
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Skalierungsfragen und Aktionssoziometriese groups, the metallopeptidases represent the most diverse group, comprising 25 different families (1,2). Most of the Zn-binding metallopeptidases, named zincins, have the HEXXH motif for Zn-binding. Some other Zn-binding motifs have been defined, as there are the HXXEH, the HXXE, and the HXH motif
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