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Titlebook: Cellular Mechanisms in Airways Inflammation; Clive P. Page,Katharine H. Banner,Domenico Spina Book 2000 Springer Basel AG 2000 asthma.brea

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发表于 2025-3-21 18:20:15 | 显示全部楼层 |阅读模式
书目名称Cellular Mechanisms in Airways Inflammation
编辑Clive P. Page,Katharine H. Banner,Domenico Spina
视频video
丛书名称Progress in Inflammation Research
图书封面Titlebook: Cellular Mechanisms in Airways Inflammation;  Clive P. Page,Katharine H. Banner,Domenico Spina Book 2000 Springer Basel AG 2000 asthma.brea
描述Airways inflammation is a complex biological phenomenon resulting from the recruitment and activation of numerous cell types.Airways inflammation contributes to the pathophysiology of airways disease. An understanding of the mechanisms that regulate inflammatory cell function is essential for the development of novel anti-inflammatory drugs for the treatment of common respiratory diseases such as asthma and COPD. This book provides a collection of valuable reviews on the major inflammatory cells involved in airways disease and examines the pharmacology of current anti-inflammatory drugs used in the treatment of airways disease.Moreover, an insight into the development of emerging drug therapies is also highlighted. This book is a must for the library of any researcher or clinician interested in the pathophysiology of airways disease.
出版日期Book 2000
关键词asthma; breathing; cell; diseases; inflammation; macrophages; pathophysiology; pharmacology; physiology; ther
版次1
doihttps://doi.org/10.1007/978-3-0348-8476-1
isbn_softcover978-3-0348-9583-5
isbn_ebook978-3-0348-8476-1Series ISSN 1422-7746 Series E-ISSN 2296-4525
issn_series 1422-7746
copyrightSpringer Basel AG 2000
The information of publication is updating

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Role of basophils in airways inflammation, mammalian species analysed so far, basophils and mast cells are the only cells that synthesize histamine and express plasma membrane receptors that bind with high affinity the Fce portion of IgE (FcεRI) [.]. Human basophils derive from precursors that originate in the bone marrow and in foetal live
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Platelets, has been focussed on these blood elements. This large research effort has lead to a series of significant advances in the understanding of the physiology of platelets and on their participation not only to haemostasis and thrombosis but also to non-haemostatic processes.
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Neutrophils,bes was recognised by Elie Metchnikoff in the 19th century, but in recent years the double-edged nature of the inflammatory response has been recognised. Despite their beneficial role in host defence, neutrophils and their pro-inflammatory products are increasingly implicated in the pathogenesis of
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Eosinophils in asthma,erlying this exaggerated responsiveness are still unclear, there is a considerable body of evidence to suggest that mucosal inflammation of the airways is of central importance. Perhaps the most common pathological finding is that of an increased number of eosinophils in the lung mucosa. It is curre
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Drugs that reduce airways inflammation,hma. The recognition that asthma is a chronic inflammatory disease of the airways has prompted recent guidelines being issued on the treatment of asthma, all of which have highlighted the need for earlier intervention with anti-inflammatory drugs. This chapter reviews the evidence that glucocorticos
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