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Titlebook: Cellular Lipid Binding Proteins; Jan F. C. Glatz Book 2002 Springer Science+Business Media Dordrecht 2002 DNA.Lipid.biochemistry.gene expr

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Analysis on the phenotype of E-FABP-gene knockout mice,eu of the cornified cell layer in the epidermis. In view of this importance in the skin, we examined the phenotype of epidermal fatty acid binding protein (E-FABP)-deficient mice. In spite of total lack of E-FABP expression in the various tissues of E-FABP deficient mice, these animals appeared norm
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Sterol carrier protein-2: Not just for cholesterol any more,hese cells, a potential role for SCP-2 in fatty acid uptake and trafficking has not been appreciated. Certainly, recent experiments have shown that SCP-2 binds fatty acids . with an affinity similar to that observed for fatty acid binding proteins. Because of the ubiquitous tissue distribution of SC
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Alternative lipid mobilization: The insect shuttle system, to energy generation for sustained locomotion in mammals, the work accomplished by non-stop flight activity is powered by oxidation of free fatty acids (FFA) derived from endogenous reserves of triacylglycerol. The transport form of the lipid, however, is diacylglycerol (DAG), which is delivered to
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Giant membrane vesicles as a model to study cellular substrate uptake dissected from metabolism,iver, skeletal muscle and adipose tissue. We investigated which cell types and which plasma membrane regions are involved in giant vesicle formation and we examined the presence of transporters for metabolic substrates. Analysis of giant vesicles with markers specific for distinct cell types and dis
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Peroxisome proliferator-activated receptors: Lipid binding proteins controling gene expression,g of the nineties the three isoforms (PPARα, β/δ and γ, encoded by different genes) have been implicated in the regulation of almost every single aspect of lipid metabolism and, consequently, in diseases that involve disturbances in lipid metabolism (obesity, diabetes, atherosclerosis, cardiac failu
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New insights into the fatty acid-binding protein (FABP) family in the small intestine, acids (LCFAs), bile acids (BAs) or retinoids. In the small intestine, three different FABP isoforms exhibiting a high affinity for LCFAs and/or BAs are expressed: the intestinal and the liver-type (I-FABP and L-FABP) and the ileal bile acid-binding protein (I-BABP). Despite of extensive investigati
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