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Titlebook: Cell Migration in Inflammation and Immunity; Methods and Protocol Daniele D’Ambrosio,Francesco Sinigaglia Book 2003 Humana Press 2003

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https://doi.org/10.1007/b137387static as well as inflammatory conditions (.,.). Novel subsets of lymphocytes have been identified on the basis of their profile of chemokine-receptor expression (.–.). The ability of a cell population to adhere and migrate in response to a chemokine can be tested making use of several established i
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Pickup and Delivery Selection Problems,r many different conditions, such as inflammation, invasion and metastasis, normal recirculation of blood cells, and so forth. Cells belonging to the immune system provide a typical example of cells in which migration is a critical feature for them to exert their physiological function (.–.). Leukoc
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Pickup and Delivery Selection Problems,ting different cell functions, including migration, adhesion, proliferation, differentiation, apoptosis, and specific gene expression. A central role in the integrin-triggered signaling cascades is played by activation of the small GTP-binding proteins belonging to the Ras and Rho families (.–.).
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Transport in Freight Carrier Networks,he elucidation of the mechanisms responsible for leukocyte recruitment is critical for the development of novel therapeutic approaches for these conditions. Among the molecules implicated in regulating leukocyte trafficking are the chemokines, low-molecular-weight secreted molecules that interact wi
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Transport in Freight Carrier Networks,ocyte and endothelial cells. First, leukocytes in the mainstream of blood flow come into contact with the endothelium and they roll along the endothelial surface via a group of molecules termed the selectins (.). Next, rolling leukocytes are activated by pro-inflammatory molecules presented on the e
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