Titlebook: Cell Cycle in Development; Jacek Z. Kubiak Book 2011 Springer-Verlag Berlin Heidelberg 2011 Cell Cycle Regulation.Embryogenesis

Interlocking

Traditional and Performing ArtsA2-deficiency is marked by early embryonic lethality; thus, understanding the function of cyclin A2 in the adult germ line awaits conditional mutagenesis or other approaches to knock down its expression.

Dissonance

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The Spindle Assembly Checkpoint: Clock or Domino?,is not only a pure checkpoint pathway, but plays a constitutive role in every cell cycle. Here, we review our current knowledge of how the spindle assembly checkpoint is integrated into the cell cycle machinery, and discuss some of the questions that have to be addressed in the future.

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The Role of RanGTP Gradient in Vertebrate Oocyte Maturation,ors including cyclin B1, Wee2, and Cdc25B between the oocyte cytoplasm and germinal vesicle (GV) is required for normal resumption of meiosis. After GVBD in mouse oocytes, RanGTP gradient is required for timely meiosis I (MI) spindle assembly and provides long-range signal directing egg cortex diffe

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Function of the A-Type Cyclins During Gametogenesis and Early Embryogenesis,A2-deficiency is marked by early embryonic lethality; thus, understanding the function of cyclin A2 in the adult germ line awaits conditional mutagenesis or other approaches to knock down its expression.

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Cell Cycle Adaptations and Maintenance of Genomic Integrity in Embryonic Stem Cells and Induced Pluication. Furthermore, ES cells express higher level of DNA repair proteins, and exhibit enhanced repair of multiple types of DNA damage. Similarly to ES cells, induced pluripotent stem (iPS) cells are poised to proliferate and exhibit lack of G./S cell cycle arrest, extreme sensitivity to DNA damage