Titlebook: Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems; Antonio Giordano,Umberto Galderisi Book 2010 Springer Scie

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The Basic Helix-Loop-Helix Transcription Factors in Neural Differentiationth progeny re-enter the cell cycle. By mid-gestation, the cells initiate neurogenesis by adopting a mode of asymmetric cell division, in which one daughter cell differentiates into a neuron while the other continues to cycle in the ventricular zone. Neural stem cells gradually alter their characteri

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The Neural Stem Cells central nervous system (CNS) showing complex patterns of gene expression that may vary in both space and time. Endogenous stem cells residing within CNS germinal niches might concur to nervous system repair owing to their ability to drive neurogenesis and gliogenesis during adulthood. Nevertheless,

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Cell Cycle and Differentiation in Vesselsing waste products. Vasculature also mediates signals for correct organogenesis. Not surprisingly therefore, vessels are critical for organ growth in the embryo and for repair of wounded tissue in the adult. In this chapter we will focus in particular on molecular factors involved in differentiation

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Cell Cycle Regulation in Myogenesis by the Rb protein, together with p21 and other inhibitors of cell cycle progression. The subsequent activation of muscle-specific promoters at the onset of differentiation is regulated by myogenic bHLH transcription factors, such as MyoD. MyoD protein binds DNA and recruits coactivators and corepre