Titlebook: Cell Biology of Extracellular Matrix; Second Edition Elizabeth D. Hay Book 1991 Springer Science+Business Media New York 1991 Embryo.biolog

泄露

Book 1991view of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first

歌剧等

ver the review of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first 978-1-4613-6680-5978-1-4615-3770-0

Ethics

Introductory Remarksre a consideration of the extracellular matrix (ECM): its composition, role in development, and relationship to the cell surface. The ECM is the relatively stable structural material that lies under epithelia and surrounds connective tissue cells, but the idea that the ECM is an inert supporting mat

Inculcate

CollagenDuring the past 10 years, however, it has become obvious that collagen comprises a large heterogeneous class of molecules, some with the structural properties classically attributed to “collagen,” but numerous others with additional properties. Vertebrates contain at least 15 different types of coll

Ergots

acquisition

The Elastic Fiberevolved to satisfy this requirement, including resilin in arthropods, abductin in molluscs, and elastin in the vertebrates (.). Phylogenetic studies have shown that elastin occurs only in vertebrates and arose first in cartilaginous fish where its appearance coincides with the achievement of a fully

Compass

Fibronectin and Other Cell Interactive GlycoproteinsFor example, fibronectin helps to mediate cell adhesion, embryonic cell migration, and wound healing, while laminin can promote processes as diverse as axonal outgrowth, maintenance of the polarized, differentiated phenotype of epithelial cells on a basement membrane, and metastasis. Each of these g

上流社会

Proteoglycansmost cases, PG metabolism is in steady state, i.e., biosynthesis of new molecules balances the catabolism of older molecules such that a constant concentration of PGs is maintained in a particular compartment over time. Cells in mature connective tissues devote a large proportion of their metabolic

泥瓦匠

Collagen Biosynthesisas well as complex interactions between primary collagen translation products and several cotranslational and posttranslational modifying enzymes (for review, see .; .; .; .). Although the total number of genes that code for collagenous polypeptides has not yet been established, more that 25 genes h

FEAS

Matrix Assemblyh, repair, or regeneration. They are complex events which ascend the biological hierarchy from molecular interactions among adjacent molecules to macroscopic interactions among adjacent tissues. The multiple levels of organization involved in matrix assembly from molecules to final structure, while