Titlebook: Cell Biology and Translational Medicine, Volume 14; Stem Cells in Lineag Kursad Turksen Book 2021 The Editor(s) (if applicable) and The Aut

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Pluripotent Stem Cell Derived Neurons as In Vitro Models for Studying Autosomal Recessive Parkinson vivo using induced pluripotent stem cell (iPSC) technology and are discussed here. PD pathophysiology is not faithfully replicated by animal models, and, therefore, nigral dopaminergic neurons generated from iPSC serve as improved human cellular models. With no cure to date and treatments aiming at

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Stem Cell Applications in Lysosomal Storage Disorders: Progress and Ongoing Challenges,rreversible organ damage has occurred..Here, we provide an overview of the known effects of LSDs on stem cell function, as well as a synopsis of available stem cell-based cell and gene therapies that have been/are being developed for the treatment of LSDs. We discuss the advantages and disadvantages

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Eosinophils as Major Player in Type 2 Inflammation: Autoimmunity and Beyond,opic dermatitis, allergic rhinitis, and asthma. They are also fundamentally involved in autoimmune disorders such as eosinophilic esophagitis, eosinophilic gastroenteritis, acute and chronic eosinophilic pneumonia, and eosinophilic granulomatosis with polyangiitis. In infections, eosinophils are inv

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0065-2598 ed to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 14th volume of a continuing series..978-3-030-80494-7978-3-030-80492-3Series ISSN 0065-2598 Series E-ISSN 2214-8019

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