Titlebook: Cartilage: From Biology to Biofabrication; Mohamadreza Baghaban Eslaminejad,Samaneh Hosseini Book 2023 The Editor(s) (if applicable) and T

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Widely Used Biomaterials in Cartilage Biofabrication,eparates it from surrounding tissues and consists of an outer fibrous layer and an inner cellular layer. There are three types of cartilage with different structures and functions: hyaline cartilage, the most common type of cartilage with a smooth surface and many collagen fibrils and chondrocytes,

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Importance of 3D Printing Techniques in Cartilage Tissue Engineering,uding both scaffold-based and scaffold-free approaches implemented in cartilage tissue engineering. Recent studies have been reviewed and scaffold-based 3D printing techniques have been divided into five main categories as extrusion/microextrusion, inkjet, in-situ, laser-based, and stereolithography

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Cell Therapy as a Novel Therapeutic Approach for Cartilage Diseases,h evidence of up to 20 postoperative years supporting its use. However, certain inherent limitations with the ACI procedure have sparked a gradual shift in interest to explore the development of Mesenchymal Stem Cells (MSCs) for the treatment of such cartilage lesions. This chapter explores the role

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Extracellular Vesicles: A Potent Therapeutic Tool for Cartilage Regeneration,rticipate in cell-to-cell communication, regulating a number of cellular processes, including cell development, proliferation, and migration. Studies conducted both in vitro and in vivo have shown that EVs have the ability to regenerate cartilage. Exosomes derived from mesenchymal stem cells (MSCs)

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Stem Cells Therapy for Cartilage Regeneration in Clinic: Challenges and Opportunities,r cartilage have a poor chance of healing since it is an avascular tissue. Small defects may eventually heal on their own without treatment, but the repair tissue is inferior to the body’s own hyaline cartilage because it is made of fibrocartilage. Due to its regenerative capabilities, the idea of s

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Validation of Tissue-Engineered Constructs: Preclinical and Clinical Studies, tissue-engineering strategies to create a hopeful therapeutic approach for articular cartilage repair. The strategies used for tissue engineered articular cartilage include cell-based-engineering, scaffold-free, and cell-free approaches. Using cells sources such as autologous chondrocytes and stem

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Introduction to Cartilage Tissue: Development, Structure, and Functions,d on biomechanical characteristics. Such studies can explain relevant mechanisms which can be used in regenerative medicine and improvement of tissue engineering methods and restore tissue degeneration. This study summarizes AC composition, structure, and function through different stages of AC deve