Titlebook: Cartilage Restoration; Practical Clinical A Jack Farr,Andreas H. Gomoll Book 2018Latest edition Springer International Publishing AG, part

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The Regulatory Environment for Emerging Cartilage Repair Technologiestherapies. This protection has created hurdles for the development of new cartilage repair techniques and technologies. In the United States, the Federal Food and Drug Administration (FDA) is the body that governs the regulation of cartilage repair development. The focus of this chapter is to offer

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The Role of Stem Cells in Surgical Repairir began with benchtop research four decades ago and have taken strides in the last decade through clinical trials. This chapter provides an overview of the development of these treatments and insight into the future of stem cell therapy in cartilage repair. With an improved understanding of the his

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The Role of MSCs for Nonsurgical Treatment of OAconservative treatments is among the main reasons for the increasing demand of knee and hip replacement, as well as for the increasing interest for stem cell-based treatments, due to their anti-inflammatory, immunomodulatory, and regenerative potential and to their ability to influence positively th

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Debridementement can be used in isolation to address mechanical symptoms, for unstable chondral lesions encountered during concomitant surgeries, or as part of multistage procedures, such as autologous chondrocyte implantation. Joint debridement may involve removing loose or unstable cartilaginous flaps, loose

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Marrow Stimulation and Augmentation there are between an estimated 30,000 and 100,000 chondral repair procedures that are performed yearly in the United States. Marrow stimulation is a commonly used technique for articular cartilage repair. Marrow stimulation involves the perforation of the subchondral bone plate, most commonly with