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Titlebook: Cardiovascular Genomics; Mohan K. Rai,Julian F. R. Paton,Michael J. Katovic Book 2005 Humana Press 2005 Angiotensin II.cardiovascular.gene

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Application of Viral Gene Transfer in Studies of Neurogenic Hypertension and controllable genetic manipulation in selected areas of the brain in different species and strains, including experiments in the spontaneously hypertensive rat, an established model of hypertension. Recent evidence indicates that, in contrast to pharmacological tools that may act on any cellular
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Vigilant Vectorsinjected that waits in the heart for an ischemic attack. The vector then switches on cardioprotective genes specifically in the heart to save the cells from apoptosis and maintain cardiac performance. Using the adenoassociated virus (AAV), we have developed a double vector system (a sensor and an ef
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Gene Therapy for Celebral Arterial Diseasesncy. Several major steps, including gene transfer to cerebral arteries and alteration of gene expression, have been taken. There are several promising targets for cerebrovascular gene therapy, such as prevention of cerebral vasospasm after subarachnoid hemorrhage, stimulation of formation of collate
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Therapeutic Angiogenesis and Vasculogenesis for Tissue RegenerationManipulation of the angiogenesis program and transplantation of progenitor cells is hoped to overcome endogenous liabilities that impede appropriate healing in atherosclerotic or diabetic patients. Viral vectors represent the usual means for delivering curative genes, but new nonviral methods are ga
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25-53 - 25-92: C8H20NO4Tc - O7Tc2.H2O,illion Americans with a prevalence rate of 25–30% in the adult Caucasian population. The incidence of hypertension and complications resulting from hypertension are even greater in the African-American population. The renin-angiotensin system plays an important role in the regulation of blood pressu
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25-53 - 25-92: C8H20NO4Tc - O7Tc2.H2O,or reasons: (1) for delineating the biochemical/physiological mechanisms for BP control; and (2) for utilizing this knowledge to improve clinical management strategies for maintenance of normal physiological BP, which is an important factor in reducing the risk for susceptibility to cardiovascular d
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