| 书目名称 | Cardiac Rate and Rhythm | | 副标题 | Physiological, Morph | | 编辑 | Lennart N. Bouman,Habo J. Jongsma | | 视频video | | | 丛书名称 | Developments in Cardiovascular Medicine | | 图书封面 |  | | 描述 | In the denervated state the mammalian heart, both in vivo and in vitro, is excited at very regular intervals, the coefficient of variance of the interbeat intervals not exceeding 2%. The pacemaker that is the source of this regular ex citation is localised normally within the sinus node (" sino-atrial node " node of Keith and Flack), a most intriguing small piece of tissue in the caval corner of the right atrium. A small portion of this node containing a group of probably only a few thousands of cells fires spontaneously, that means without any exter nal influence to trigger their activity. The so called pacemaker cells do this by letting their membrane potential fall to the level where an action potential will start which subsequently activates surrounding cells to fire an action po tential. The first question which is tackled in this book is which processes underly this spontaneous diastolic depolarization. This is discussed in section I, concerning the fundamental properties of pacemaker cells with special refer ence to ionic membrane currents. Although views still quite differ about the exact nature of the membrane processes that cause the automatic pacemaker dis charge th | | 出版日期 | Book 1982 | | 关键词 | drugs; heart; heart rate; membrane; pacemaker | | 版次 | 1 | | doi | https://doi.org/10.1007/978-94-009-7535-4 | | isbn_softcover | 978-94-009-7537-8 | | isbn_ebook | 978-94-009-7535-4Series ISSN 0166-9842 | | issn_series | 0166-9842 | | copyright | Martinus Nijhoff Publishers, The Hague 1982 |
The information of publication is updating
|
|
发表于 2025-3-21 17:29:52
