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Titlebook: Carbohydrate-spiro-heterocycles; László Somsák Book 2019 Springer Nature Switzerland AG 2019 Spiro-annulated carbohydrate.Cycloaddition re

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Daan J.A. Crommelin,Jon S. B. de Vliegerycles can be obtained by 1,3-dipolar cycloaddition reactions between an olefin and a nitrile oxide or a nitrone. This reaction generates one C–C and one C–O bond and up to three chiral centres in one step. In the present chapter, we aim to summarize and discuss reports of these cycloadditions on sug
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Daan J.A. Crommelin,Jon S. B. de Vlieger radical chemistry. A variety of heterospiro[...]alkane bicyclic structures (. = 3–5, . = 4–6) possessing one, two, or three heteroatoms (N, O, Si, S) have been collected, in addition to three different 1,6,8-trioxadispiro-tetradecane and 1,6,8-trioxadispiro-pentadecane tricyclic systems. C(sp.)–H b
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David F. Driscoll,David F. Nicolid a hydroxyl or amine function allows access to promising heterocyclic compounds of particular interest resulting from reactions taking advantage of the electrophilic character of the cyano group and the nucleophilic character of hydroxyl and amino groups. Thus, α-hydroxynitriles (cyanohydrins) or α
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Non-Hermitian Open Chain and Periodic Chain,t to light in the ability of drug researchers to draw on an understanding of the biochemistry of naturally occurring nucleosides and to build up synthetic nucleoside analogues, which belong to the most important class of antiviral drugs and are extensively used as anticancer agents and in the treatm
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Hermitian Systems and Non-Hermitian Systems,l phthalane .-glycosides, in which a phthalane ring and sugar unit form a spiroketal framework, have garnered enormous attention from wide research areas because such a fascinating spirocycle motif is found in antibiotic natural products, i.e., papulacandins and their relatives. Moreover, recent rep
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László SomsákProvides an overview of recent developments in spirocyclization techniques adapted to carbohydrates.Presents recent advances in the utility of sugar derived spiro-heterocycles.Multi-authored volume wi
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Michiel Doorn,David Liles,Susan Thorneloecedented polyhydroxy-azaspiranes, the structures and syntheses of which are presented in this chapter. Special attention is paid to the key steps involved in the generation of the pivotal quaternary spiro atom.
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