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Titlebook: Capillary Electrophoresis Guidebook; Principles, Operatio Kevin D. Altria Book 1996 Humana Press 1996

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Capillary Gel Electrophoresisein and complex carbohydrate molecules (.,.). For relatively short single-stranded DNA units (i.e., oligonucleotides) and carbohydrate molecules, there is a need to separate by a single base difference (for DNA sequencing) (.) or even for identical chain length with a different sequence (identificat
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Chiral Separations by Capillary Electrophoresisns have been achieved in Free Solution Capillary Electrophoresis (FSCE) employing cyclodextrins (CDs) as chiral selectors. This is because of their ready availability and broad applicability. Chiral resolutions have also been achieved in micellar electrokinetic chromatography (MEKC) through the use
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Capillary Electrochromatographyf a high-pressure mechanical pump. However, under certain conditions, the mobile phase can be forced to migrate through the chromatographic medium by the application of an electric field. This phenomenon of electrically induced fluid flow is commonly referred to as electro-osmosis or electro-osmotic
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Analysis of Bases, Nucleosides, and (Oligo)nucleotides by Capillary Electrophoresislogy associated with capillary gel electrophoresis (CGE) is covered elsewhere in this book (.) and in recent reviews (.–.). A number of nucleosides and nucleotides have been used in chemotherapy as antiviral agents, e.g., 3′-azido-3′-deoxythymidine (azT), and 2′,3′-dideoxyinosine (ddI), and 2′,3′-di
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Application of Capillary Electrophoresis to Pharmaceutical Analysisrug may be analyzed in its anionic form at high pH, and basic drugs may be tested at low pH in their cationic form. . shows the efficient separation of a test mixture containing 11 basic drugs using a simple low-pH electrolyte. Zwitterionic drugs (those containing both acidic and basic groups) may b
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Separation of Peptides and Protein Digests by Capillary Electrophoresisences between peptides (.,.). Recently, however, capillary electrophoresis (CE) has increasingly been used for peptide analysis. In capillary zone electrophoresis (CZE), the separation mechanism is based mainly on differences in charge-to-mass ratios, and since peptides are amphoteric, they are idea
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The Industrial Context of Newspaper Firms, a plot of UV absorbance vs time. Therefore, HPLC data handling and peak integration packages are generally applicable to CE. Main component assay may be performed using external and internal standardization or by standard addition. Impurity data can be calculated and reported as either % w/w or % area/area.
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