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Titlebook: Cancer of Unknown Primary; Alwin Krämer,Harald Löffler Book 2016 The Editor(s) (if applicable) and The Author(s), under exclusive license

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楼主: Coenzyme
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Biologic Features of CUP,ewed, followed by an overview of specific genetic aberrations in CUP tumors, which are likewise less well characterized than in other solid cancers, with somewhat contradictory findings published even regarding important tumor suppressor and oncogenes like TP53 or EGF receptor. Finally, we discuss p
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Treatment of Disseminated CUP,therapy is not well documented but may be effective in selected patients. New treatment options are expected to result from gene expression profiling and recent developments in immunotherapy (see Chaps. 11 and 12).
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Novel Diagnostic and Therapeutic Strategies in the Management of Patients with Cancers of Unknown Ped directed at that cancer type. This approach represents a new paradigm for the management of CUP. Empiric chemotherapy should no longer be routinely administered to all CUP patients but may be reserved for the few without a single tissue of origin diagnosis..Future therapy for patients with metast
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https://doi.org/10.1007/978-3-642-20850-8mic status may be other risk factors. Familial risk is another established risk factor with important implications for disease mechanisms. CUP associated with many cancers in family members, including cancers of the lung, liver, and kidney. The cause of death for many CUP patients was apparently the
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