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Titlebook: Cancer in Children; Clinical Management Paul A. Voûte,Ann Barrett,Malte K. Neidhardt Book 1986Latest edition Springer-Verlag Berlin Heidelb

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Oncogenes and Chromosomal Aberrationsd cytogenetic techniques in studying various tumours have led to the conclusion that most cancers have a chromosomal defect, often specific and therefore clinically relevant for diagnosis and prognosis [2, 3].
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Delayed Consequences of Therapys and our experience in children is therefore particularly limited with regard to very late disabilities arising as a result of treatment given 20–40 years earlier. It is our responsibility as paediatric oncologists to prepare the way now for the acquisition of future knowledge regarding any such ad
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s been a tremendous improvement in the treatment of cancer in children, and there is hope for even further success in this fight. We are convinced that this book and the series it is introducing will help us to make a concerted response to the challenge of cancer.978-3-540-15342-9978-3-642-96889-1
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Pharmacology of Cytostatic Drugs site, be it tumour-cell membrane, nuclear DNA or nucleotides; that duration of exposure can then be regulated; and that the drug or drugs can eventually be cleared from the target site by metabolism or excretion. The application of such theory to the human situation is impossible without knowledge
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Surgical Oncology in Childreny possible in early localized disease, and with most of the childhood cancers survival was less than 20% [1]. Radiotherapy was the first effective nonsurgical treatment used mainly for surgically inaccessible sites or palliatively in advanced disease.
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