Titlebook: Cancer Stem Cells: New Horizons in Cancer Therapies; Surajit Pathak,Antara Banerjee Book 2020 The Editor(s) (if applicable) and The Author

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New Frontiers in Technological Literacye, when unique cell markers, which are specific to a particular type of tumor was deciphered. Importantly, the characterization and evaluation of key signalling pathways in CSCs are critical, as emerging evidence indicate that CSCs play a key role in dissemination during cancer metastasis or relapse

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New Frontiers in Technological Literacyas seen evidences that have clearly revealed the critical role of PCa stem cells (PCSCs) in PCa. Metastasis, till date, remains a big challenge in the treatment of these cancer types due to limited survival advantage of the second-generation drugs as observed in sufferers. Molecular mechanisms revea

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Eco-Technological Literacy for Resiliency, miR-214, miR-21, etc.) which not only act as either oncomirs or tumor suppressors but also regulate stemness property along with epithelial-mesenchymal transition, invasion, and metastasis. This study also enlightens the involvement of various crucial signalling pathways (e.g., Notch, Wnt, and PI3

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New Frontiers in Technological Literacym SCs or from non-stem cells that acquire self-renewal potential. Likely SCs, CSCs express regulatory factors of self-renewal, such as SOX2, MYC, and OCT4, and some common “stemness” pathways, such as Wnt signaling. In contrast, they could not be multipotent and lead to single lineage tumors, such a

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Eco-Technological Literacy for Resiliency tumour, which leads to increased invasiveness of these cells. These unique subpopulations of cells can communicate with their tumour microenvironment (TME) or niche, and stimulate their niche to secrete several intrinsic factors, which triggers neoangiogenesis to promote metastasis. The multipotent

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From Cybereducation to Cyberactivismout life, improvement of treatment modalities based on CSC therapies holds wish for better overall survival and better quality of life of cancer sufferers, specifically for patients with metastatic disorder. Therefore, in this book chapter, we have mainly discussed aberrant regulation of gene expres

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