书目名称 | Cancer Proteomics |
副标题 | From Bench to Bedsid |
编辑 | Sayed S. Daoud |
视频video | |
概述 | Comprehensive look at the use of proteomic strategies in cancer therapy.Covers all the latest technologies used in proteomics.Includes in-depth information on the human proteome and the role of the FD |
丛书名称 | Cancer Drug Discovery and Development |
图书封面 |  |
描述 | .This book provides the reader with broad perspectives and breadth of knowledge on current topics related to the use of proteomic strategies in cancer therapy as well as anticipated challenges that may arise from its application in daily practice. The book is divided into 4 parts. The first part begins with the current technologies used in proteomics that allow for protein profiling and for the identification of druggable targets in human samples. Mass spectrometry based protein characterization and protein microarrays hold great promise of predicting response to specific drugs in cancer therapy. The second part deals with the use proteomics in cell signaling. At the present, the pharmaceutical and biotechnology industries have many potentially useful small molecule inhibitors of many pathways important in cancer that have yet to be taken to clinical trials. Understanding protein-protein interaction and posttranslational modifications through proteomics will likely make it much more feasible to do effective clinical trials of these small molecules alone and in combinations to overcome drug resistance and improve patient care. The third part of the book moves from signaling to actua |
出版日期 | Book 2008 |
关键词 | Bioinformatics; Cancer Research; Carcinom; Oncology; Proteomics; Translation; classification; diagnostics; p |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-59745-169-7 |
isbn_softcover | 978-1-61737-807-2 |
isbn_ebook | 978-1-59745-169-7Series ISSN 2196-9906 Series E-ISSN 2196-9914 |
issn_series | 2196-9906 |
copyright | Humana Press 2008 |