| 书目名称 | Cancer Immunotherapy at the Crossroads |
| 副标题 | How Tumors Evade Imm |
| 编辑 | James H. Finke,Ronald M. Bukowski |
| 视频video | |
| 概述 | Includes supplementary material: |
| 丛书名称 | Current Clinical Oncology |
| 图书封面 |  |
| 描述 | Leading investigators and clinicians detail the different mechanisms used by tumors to escape and impair the immune system and then spell out possible clinical strategies to prevent or reverse tumor-induced immune dysfunction. The authors review the mechanisms of immune dysfunction and evasion mechanisms in histologically diverse human tumors, focusing on tumor-induced molecular defects in T cells and antigen-presenting cells (dendritic cells and tumors), that may serve as biomarkers for patient prognosis. They discuss the means by which these immune functions may be protected or restored in order to more effectively support the process of tumor rejection in situ. Cutting-edge techniques are outlined with the capacity to monitor the strength and quality of patients‘ immune responses using immunocytometry, MHC-peptide tetramers combined with apoptosis assay, ELISPOT assay, and detection of MHC-TAA peptide complexes on tumor cells. |
| 出版日期 | Book 2004 |
| 关键词 | apoptosis; brain tumors; carcinoma; cell; immunotherapy; lymphocytes; lymphoma; renal cell carcinoma; transp |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-59259-743-7 |
| isbn_softcover | 978-1-4684-9844-8 |
| isbn_ebook | 978-1-59259-743-7Series ISSN 2364-1134 Series E-ISSN 2364-1142 |
| issn_series | 2364-1134 |
| copyright | Springer Science+Business Media New York 2004 |
发表于 2025-3-21 16:19:02
