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Titlebook: Cancer Gene Therapy; David T. Curiel,Joanne T. Douglas Book 2005 Humana Press 2005 cancer treatment.clinical trial.gene therapy.gene trans

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https://doi.org/10.1007/978-3-642-00909-9potential opportunities in this area by providing new methods for stimulating the immune response. Among the array of techniques under development for clinical application, nucleic acid or polynucleotide vaccines have emerged as a novel and effective method of inducing tumor antigen-specific immune responses.
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Junzo Watada,Shuming Wang,Witold Pedryczvirus type 1 [HSV-1], adenovirus, vaccinia virus), naturally attenuated (e.g., Newcastle disease virus), or nonpathogenic in humans (e.g., reovirus), so they replicate selectively in tumor cells, but do not harm normal tissues ..
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Suicide Gene Therapy,natives aimed at enhancing the selectivity of cancer chemotherapy for solid tumors rely on targeting cancer cells with chemoimmunoconjugates, antibody-directed enzyme prodrug therapy (ADEPT) ., or gene-directed enzyme prodrug therapy (GDEPT) ..
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Dendritic Cells,e the environment for “danger” or foreign antigens. If such is encountered, they migrate to locally draining lymph nodes, during which transit they undergo a process of maturation. In maturation, their capacity to acquire antigen is lost simultaneous with their acquisition of an enormous capacity to prime naïve T cells.
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