Titlebook: Cancer Gene Therapy; David T. Curiel,Joanne T. Douglas Book 2005 Humana Press 2005 cancer treatment.clinical trial.gene therapy.gene trans

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A. Bonso,A. Rossillo,R. Valente,A. Ravielet is the history of the last few years that is largely dictating the research directions that will likely be both profitable and permitted in the future. This brief introductory chapter outlines the early days of cancer gene therapy—the successes and the setbacks—and suggests how the remaining chall

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A. Bonso,A. Rossillo,R. Valente,A. RavieleTheodor Boveri . suggested “the presence of definite chromosomes which inhibit division.” Writing in 1914 (translation published in 1929), Boveri ventured that “cells of tumors with unlimited growth would arise if those ‘inhibiting chromosomes’ were eliminated.” Over half a century later, molecular

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https://doi.org/10.1007/978-88-470-2087-0nic genes (Fig. 1). In the past, the term . included several distinct but related approaches, including classical antisense or anticode, ribozyme or catalytic ribonucleic acid (RNA), triplex or antigene, and aptamer technologies (Table 1). A unified terminology has not yet been developed to describe

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