Titlebook: Cancer Gene Profiling; Methods and Protocol Robert Grützmann,Christian Pilarsky Book 2016Latest edition Springer Science+Business Media New

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Anna Swiatek,Leszek Jaworski,Lukasz Tomasikcing, allows us to establish molecular portraits of cancer cells with unprecedented accuracy. This generates hope and justifies anticipation that disease diagnosis, prognosis, and the choice of treatment will be adapted to the individual needs of patients based on molecular evidence..Preoperative tr

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Nomadic

Functional Materials and Informationta-data such as protein-protein interaction (PPI) information into the analyses helps in the identification and prioritization of genes from these screens..Here, we describe a computational approach that identifies genes prognostic for outcome by combining gene profiling data from any source with a

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Reducing of Complexity through Integrationpment of multiple types of cancer. As these gene products typically do not exist in normal cells, they represent valuable prognostic and therapeutic targets. Advances in next-generation sequencing and computational approaches have greatly improved our ability to detect and identify fusion genes. Nev

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New Materials in Building and Public Worksroughput sequencing technologies offer a way to investigate individual chimeric transcripts and the systematic information of associated gene expressions about underlying genome structural variations and genomic interactions. The detection methods of finding chimeric transcripts from massive amount

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Curmudgeon

Target Gene Discovery for Novel Therapeutic Agents in Cancer Treatment,drugs, and (3) to identify appropriate combinations with established drugs..Here, we describe several in vitro assays applicable to characterize different characteristics of tumor cells. Furthermore, we present a protocol for establishing a reporter gene system for in vivo imaging, allowing for the study of drug effects in small animal models.

GUILT

Meta-analysis of Cancer Gene Profiling Data,ta-data such as protein-protein interaction (PPI) information into the analyses helps in the identification and prioritization of genes from these screens..Here, we describe a computational approach that identifies genes prognostic for outcome by combining gene profiling data from any source with a network of known relationships between genes.

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