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Titlebook: Cancer Gene Networks; Usha Kasid,Robert Clarke Book 2017 Springer Science+Business Media New York 2017 translational cancer biology.cancer

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Neuzuwanderung in Duisburg-Marxloh of oncogenes (e.g., NFAT5, MALAT1, MET, FOXA1, KRAS, S100P, OSTF1) and glutamate transporter gene SLC1A1. TNFAIP8 knockdown cells also exhibited decreased expression of multiple onco-proteins (e.g., PIK3CA, SRC, EGFR, IL5, ABL1, GAP43), and increased expression of the orphan nuclear receptor NR4A1
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Neuzuwanderung in Duisburg-MarxlohConsonant with this knowledge of the multifactorial mechanistic basis of drug sensitivity and resistance is the application of network-based approaches for the identification of molecular (multi-)feature signatures associated with desired (multi-)drug phenotypic profiles. This chapter illustrates th
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https://doi.org/10.1007/978-981-10-6787-7body to the biomarker of interest. That antibody’s titer can then be determined quantitatively for each patient, allowing for the statistical assessment and validation of the diagnostic or prognostic utility of that particular antigen. As the technology matures and the availability of validated, pla
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Book 2017 as well as in the practice of personalized oncology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and ti
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Book 2017ps on troubleshooting and avoiding known pitfalls.. . .Authoritative and cutting-edge, .Cancer Gene Networks. aims to ensure successful results in the further study of this evolving and vital field. Ultimately these efforts will guide development of transformative strategies for cancer diagnosis and treatment..
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https://doi.org/10.1007/978-3-658-41313-2atform, the protocols can be adapted for general use with CRISPR/Cas or other engineered nucleases. The transfection procedures described could also be used for additional applications, such as overexpression or lineage tracing studies.
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https://doi.org/10.1007/978-3-658-41313-2 unequivocally detecting cytoplasmic protein delivery and quantifying protein transformation efficiency. Finally, we present a protocol for efficient protein delivery to the cytosol validated using these methods.
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