Titlebook: Cancer Epigenetics for Precision Medicine; Methods and Protocol Ramona G. Dumitrescu,Mukesh Verma Book 2018 Springer Science+Business Media

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https://doi.org/10.1007/978-3-642-98980-3n DNA methylation patterns that play a critical role in cancer development. Specific epigenetic changes in esophageal, hepatic, and colorectal cancers have been detected in blood samples and proposed to be used clinically as epigenetic biomarkers for diagnosis and prognosis of these cancers. Also, g

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Richard Petersen,Alfred Andreassen response escape, such as classical HLA proteins and related APM (antigen presentation machinery) with their epigenetic changes contribute to the tumor development process, either to tumor progression or regression, depending on the immune effector cells that are in play.

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Richard Petersen,Alfred Andreassenon age or the extent of acceleration with mortality and various aging-related conditions, even after accounting for differences in chronological age and other risk factors. Although epigenetic profiles are known to be tissue-specific, both target tissue- and multiple tissue-derived estimates appear

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Early Epigenetic Markers for Precision Medicinecific methylation markers important for CRC detection and in fact clinical assays evaluating the methylation status of SEPT19 gene and vimentin, became commercially available. Furthermore, some epigenetic changes detected in gastric washes have been suggested as potential circulating noninvasive bio

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Role of Microbiome in Carcinogenesis Process and Epigenetic Regulation of Colorectal Cancer and complexity of microbial interaction in initiating the development of CRC. In the multifaceted processes of colonic carcinogenesis, gradual alteration of microbiota along with their microenvironment and the potential oncopathogenic microbes mediated modulation of cancer therapy and other factors

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Epigenome-Based Precision Medicine in Lung Cancermvent the problems of tumor heterogeneity and drug resistance by affecting the expression of several hundred target genes. This review highlights precision medicine using an innovative approach of epigenetic priming prior to conventional standard therapy or targeted cancer therapy in lung cancer.

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Effects of Dietary Nutrients on Epigenetic Changes in Cancer aimed at developing nutriceuticals and drugs as cancer therapies. Clinical studies are needed to evaluate the optimum doses of dietary compounds, the safety profile of dosages, to establish the most efficient way of administration, and bioavailability, in order to maximize the beneficial effects al