| 书目名称 | Cancer Drug Safety and Public Health Policy |
| 副标题 | A Changing Landscape |
| 编辑 | Charles Bennett,Courtney Lubaczewski,Bartlett With |
| 视频video | |
| 概述 | Analyzes current policy trends regarding cancer drug safety.Explains the policy implications of recent legal settlements.Covers issues in identification and reporting of ADRs |
| 丛书名称 | Cancer Treatment and Research |
| 图书封面 |  |
| 描述 | .This book offers a wide-ranging description and analysis of recent developments and current trends in health policy with regard to cancer drug safety. The book opens with an overview of pharmacovigilance for cancer blockbuster drugs, covering both general considerations and efforts to develop a structured framework for the identification and reporting of adverse drug reactions (ADRs). A number of important examples of serious ADRs to hematology and oncology drugs are then reviewed, with evaluation of the lessons learned and the policy implications of the ensuing legal cases and their settlements. Further, the difficulty of reporting such blockbuster side effects in the medical literature is explored in an empirical study. Significant advances have been achieved in analytic methods for the identification of ADRs, and here there is a particular focus on the value of optimal discriminant analysis. Finally, the impacts on pharmacovigilance and drug safety of the huge fines paid under the U.S. False Claims Act relating to the defrauding of governmental programs also receive careful attention – these fines are playing an important role in changing the landscape for pharmaceutical safety |
| 出版日期 | Book 2022 |
| 关键词 | Health Policy; Novel Informatics; Pharmacovigilance; Cancer Drug Safety; Cancer Blockbuster Drogs; Pharma |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-031-04402-1 |
| isbn_softcover | 978-3-031-04404-5 |
| isbn_ebook | 978-3-031-04402-1Series ISSN 0927-3042 Series E-ISSN 2509-8497 |
| issn_series | 0927-3042 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 16:49:00
