Titlebook: Cancer Drug Discovery; Science and History Kyu-Won Kim,Jae Kyung Roh,Chan Kim Book 2016 Springer Science+Business Media Dordrecht 2016 Hist

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Black Holes: Physics and Astrophysicsd cancer “neoplasm,” which was defined as a new mass of cells that emerges from abnormal proliferation of cells (Fig. 2.1). Thus, cancer was introduced into the field of science, was scientifically defined, and became an object of study.

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https://doi.org/10.1007/978-94-024-0844-7History of Cancer Drugs; Cancer Therapy Development; Adverse Effects of Anticancer Drugs; Cell Concept

较早

978-94-024-1417-2Springer Science+Business Media Dordrecht 2016

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,Die neue Physik fällt vom Himmel,the cell as the basic unit of all organisms. Since cells are the common structural unit of a variety of organisms including animals and plants, it was hypothesized that complex life phenomena of multicellular organisms could be understood by studying individual cells. Molecular-level research began

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Black Holes: Physics and Astrophysicsd cancer “neoplasm,” which was defined as a new mass of cells that emerges from abnormal proliferation of cells (Fig. 2.1). Thus, cancer was introduced into the field of science, was scientifically defined, and became an object of study.

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Cosmological Matter-antimatter Asymmetry, increased rapidly after the decrease in lethal infectious diseases, such as tuberculosis and typhoid, following national efforts to improve hygiene and public health. The decrease in these diseases also rapidly increased the average life span, and since the twentieth century, cancer has become one

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https://doi.org/10.1007/978-3-658-32547-3tabolic pathway. Especially, the antimetabolic anticancer drugs interfere with DNA synthesis at multiple levels by inhibiting enzymes that utilize folic acid or synthesize the precursors of pyrimidine and purine, which are necessary for cell growth. In addition, some antimetabolites are directly inc

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