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Titlebook: Cancer Chemotherapy by Infusion; Jacob J. Lokich Book 1987 Precept Press, Inc. 1987 Staging.brain tumors.carcinoma.cell.classification.cli

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Methotrexateoses of drug.. Djerassi et al were the first to illustrate responses in childhood acute leukemia with higher doses of MTX given by infusion to children refractory to conventional methotrexate treatment..
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E. Zander,M. Schattenkirchner,W. Zandernges in the therapeutic index (tumor regression versus toxicity). Other pertinent data regarding drug stability, mechanism of action, and bolus pharmacokinetics are included where appropriate, but clinical studies of continuous infusion are beyond the scope of this review.
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