Titlebook: Cancer Chemoprevention; Volume 2: Strategies Gary J. Kelloff,Ernest T. Hawk,Caroline C. Sigman Book 2005 Humana Press 2005 carcinoma.endosc

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Evaluation of Spasticity in Adultsd sufficient expenditure of resources. Ruffin and Baron (.) point out that less than 10% of subjects identified as eligible for the trials are ultimately recruited. Since prevention trial subjects are well, they may feel that they have little to gain by participating. Concerns over waiting, travel t

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Pathology of Incipient Neoplasiamor development. However, many of the morphologic and molecular abnormalities found in malignant tumors also exist in precursor or incipient lesions. New laboratory techniques, such as microdissection and polymerase chain reaction (PCR), have stimulated interest in early cancer development and events that precede invasion.

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Preclinical Animal Models for the Development of Cancer Chemoprevention Drugsays afford a strategic framework for evaluating agents according to defined criteria, and not only provide evidence of agent efficacy, but also serve to generate valuable dose-response, toxicity, and pharmacokinetic data required prior to Phase I clinical safety testing. Based on preclinical efficac